The Met Office has put out a severe weather warning, with Accrington expected to be hit by snow and ice from Storm Caroline.
A yellow weather warning has been released for Hyndburn, as temperatures are set to plummet as far as -3C this weekend.
Heavy snowfall is predicted to hit the area on Thursday evening, thawing out on Friday.
Temperatures are still expected to bite however, with a low of -1C on Friday and -2C on Saturday.
Lighter snow will pick up again in the early hours of Sunday morning, carrying on through until Monday.
With between 2cm and 5cm of snow expected to fall over the coming days, residents have been advised to take extra care when travelling.
Higher ground could see the worst of it, with predictions of between 10cm and 20cm of snowfall for some.
The cold weather is also expected to continue into the beginning of next week, with temperatures reaching -3C on Monday.
Lancashire County Council say they have begun gritting all main roads through the valley, ahead of the weekend.
Their 45-strong frontline fleet have already started gritting the roads and will continue this evening (Thursday, December 7) and throughout the night ahead of sleet and snow due to hit the county.
County Councillor Keith Iddon, cabinet member for highways and transport, said: “We’re well prepared for whatever the weather might have in store for us this winter with plenty of grit in stock and our gritting crews on standby for whenever they’re needed. We experienced a short cold snap a couple of weeks ago, but it’s due to be even colder over the coming days with forecasts for sleet and snow.
“We have the resources to treat all the A roads, all B roads, and some C roads, which adds up to around 1,500 miles – about a third of the total in Lancashire – within 4 hours of a freeze being forecast.
“However, people must remember that just because a road has been gritted it doesn’t mean it won’t be icy as it takes time and the action of tyres to mix the salt with the ice and make it work by lowering the temperature at which the water freezes. I’d ask people to use their judgement as to whether their journey is necessary. If you do decide to travel, drive according to the conditions and be aware that the state of the road can change over even relatively short distances.
“Our primary aim is to always keep the main routes moving to ensure people and goods can get where they need to go, and in severe conditions we can call on extra resources including agricultural contractors to plough rural routes and try to keep access open to more remote areas.”
You can also check which roads are gritted and links to weather forecasts at http://www.lancashire.gov.uk/winter.
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