BOTTOM club Southport upset the form book to inflict the first league defeat on leaders Accrington Stanley in 21 Conference games.
A defensive mix-up allowed Steve Daly to slot home the first on 14 minutes after he latched onto a hopeful ball forward and caught out goalkeeper Rob Elliot.
A minute later and Matty McGinn hit the post for the Sandgrounders after a poor clearance by Elliot left his goal unguarded.
However the teenage goalie made amends on 42 minutes when he saved a Neil Robinson penalty following a foul by Robbie Williams - who became the fourth Stanley player in four games to see red.
Stanley were the stronger after the break but Daly sprung the off-side trap to race free and slot the ball past Elliot to give his side a cushion.
The Reds, however, looked destined to maintain their record of scoring in every league game when Ian Craney was awarded a penalty a minute from time. However, Port keeper Steve Dickenson - who had pulled off some superb saves throughout the game - denied the midfielder with his feet to make it a miserable night for Stanley.
John Coleman's side are still 11 points clear of Hereford but have picked up two points out of nine.
"We have just got to keep working away. Ian is sick he missed the penalty and Rob is sick about conceding the first goal. I am just so disappointed we didn't maintain our record of scoring in every game.
"Now we have got to pick ourselves up."